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Reye's Syndrome Treatments


Early diagnosis and treatment are essential for a successful recovery.

Treatment may include:


Medications include:

  • Corticosteroids
  • Diuretics
  • Glucose
  • Insulin
  • Barbiturates
  • Specific treatments to reduce blood ammonia levels
    • Sodium phenylacetate and sodium benzoate
    • Dialysis
  • Ondansetron (Zofran) for severe vomiting

Arterial Catheter

If symptoms affect the brain, an arterial catheter may be inserted to monitor the pressure, carbon dioxide, and oxygen content of blood.

Pressure Monitoring

In stage 3 to 5 Reye’s syndrome, a “bolt” or other device may be used to monitor pressure within the brain.


In advanced stages, a ventilator may be used to assist with breathing.


A drainage procedure or decompression craniotomy may occasionally be needed to reduce pressure in the brain.

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Reye's Syndrome Guide

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