Symptoms of Non-Hodgkin’s Lymphoma
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If you experience any of these symptoms do not assume it is due to cancer. Most of these symptoms may be caused by other, less serious health conditions. If you experience any one of them, see your physician.
Symptoms of non-Hodgkin’s lymphoma vary, depending on where the cancer is located.
First Signs
The first signs of non-Hodgkin’s lymphoma may be any of the following:
Painless swelling of the neck, underarm, or groin – however, swollen lymph nodes occur for many reasons, most frequently infections.
Swollen Lymph Nodes

Abdominal swelling, indigestion, or stomach pain – may occur if the cancer is in the abdominal lymph tissue, blocks the intestines, or has damaged the abdominal lining and allowed fluid to collect.
Coughing or shortness of breath – may occur if the cancer starts in the chest. This can put pressure on the windpipe. If a tumor in this area compresses the superior vena cava, swelling in the head and arms may also occur.
General Symptoms
As a greater number of cancer cells develop, general symptoms may include:
- Unexplained fever
- Night sweats
- Fatigue
- Decreased appetite
- Weight loss
- Itchy skin
Sources:
Abeloff, M. Clinical Oncology , 2nd ed., Orlando, FL: Churchill Livingstone, Inc.; 2000: 2658-2701.
American Cancer Society
National Cancer Institute
Rakel, R. Conn's Current Therapy 2002 , 54th ed., St. Louis, MO: W. B. Saunders Company; 2002: 434-439.
The Leukemia & Lymphoma Society
Last reviewed February 2003 by Francine Foss, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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