Treatment
Treatment may include:
Medication
- Antibiotics—given if your doctor thinks urethral syndrome may be due to an undetected infection
-
Anesthetics
- Phenazopyridine—may be given by your doctor to ease discomfort while urinating
- Intraurethral lidocaine jelly
- Antispasmodics to decrease bladder muscle spasm (eg, oxybutynin [Ditropan])
- Antidepressants such as a tricyclic antidepressant to relieve pain
- Alpha-blocking drugs such as doxazosin (Cardura) to relax smooth muscle tone
Avoidance of Irritants
Avoid irritants that may cause urethral syndrome. Then, wait and see if your condition improves.
Surgery
Surgery may be done in cases where narrowing of the urethra is thought to be causing the urethral syndrome.
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2025 EBSCO Publishing All rights reserved.