Welcome to the EmpowHER community and thank you for coming to us for suggestions.
As you well know, vaginal atrophy is the result of decreased estrogen levels associated with menopause. Osphena use may increase your chance for getting cancer of the lining of the uterus. It can also increase the risk for having a stroke and developing blood clots.
Grandma, have you spoken with your gynecologist? Would you consider using an over-the-counter moisturizer, which can restore some moisture to your vaginal area?